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| Ann Arbor Huron High School | C | 1 | 1 | Michigan Regional 9 | Ann Arbor Public Schools | MI |
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| Ann Arbor Pioneer High School | C | 3 | 3 | Michigan SO Region 9 | Ann Arbor Public Schools | MI |
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| Centerville High School | C | 2 | 2 | Western Ohio Regional Tournament | Centerville City Schools | OH | |
| Detroit Country Day School | C | 2 | 2 | Oakland County - MI Region 6 | DCDS | MI |
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| International Academy - Central | C | 3 | 3 | | Bloomfield Hills School District | MI |
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| International Academy East | C | 1 | 1 | Oakland County - MI Region 6 | Troy School District | MI | |
| Lake Central High School | C | 2 | 2 | Valpo Regional | Lake Central School Corporation | IN | |
| Mason High School | C | 3 | 3 | Southwestern Ohio Science Olympiad | Mason City Schools | OH |
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| Mentor High School | C | 2 | 2 | Northeast & Northern Ohio Regional Tournament | Mentor Public Schools | OH | |
| Northview High School | C | 3 | 3 | BGSU Northwest Ohio Regional | Sylvania Schools | OH |
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| Northville High School | C | 2 | 2 | | Northville | MI | |
| Novi High School | C | 2 | 2 | Oakland County - MI Region 6 | Novi Community School District | MI |
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| Oak Harbor Senior High School (OHHS) | C | 1 | 1 | BGSU Northwest Ohio Regional | Benton Carroll Salem School District | OH | |
| Okemos High School | C | 2 | 2 | Michigan Science Olympiad-R11 | Okemos Public Schools | MI | |
| Olentangy Orange High School | C | 3 | 3 | Central Ohio Regional Tournament | Olentangy Local Schools | OH | |
| Ottawa Hills High School | C | 2 | 2 | BGSU Northwest Ohio Regional | Ottawa Hills Local Schools | OH | |
| Piqua High School | C | 1 | 1 | Western Ohio Regional Tournament | Piqua City Schools | OH | |
| Rocky River High School | C | 1 | 1 | Northeast & Northern Ohio Regional Tournament | Rocky River City School District | OH | |
| Saline High School | C | 3 | 3 | Michigan Science Olympiad Region 9 | Saline Area Schools | MI |
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| Shady Side Academy | C | 1 | 1 | Southwest Region at PennWest California | Fox Chapel | PA | |
| Shawnee High School | C | 2 | 2 | BGSU Northwest Ohio Regional | Shawnee Local Schools | OH | |
| Solon High School | C | 3 | 3 | Northeast & Northern Ohio Regional Tournament | Solon City Schools | OH | |
| Springfield High School | C | 2 | 2 | BGSU Northwest Ohio Regional | Springfield Local Schools (Lucas County) | OH | |
| St. Francis de Sales | C | 1 | 1 | BGSU Northwest Ohio Regional | Diocese of Toledo | OH | |
| St. Ignatius High School | C | 1 | 1 | Northeast & Northern Ohio Regional Tournament | Private1 | OH | |
| Sylvania Southview High School | C | 3 | 3 | BGSU Northwest Ohio Regional | Sylvania City | OH | |
| Troy Athens High School | C | 2 | 2 | | Troy School District | MI | |
| Troy High School | C | 2 | 2 | Oakland County - MI Region 6 | Troy | MI | |
| Washtenaw International High School | C | 1 | 1 | MI Regional 09 | WEOC | MI | |
| Westlake HS | C | 3 | 3 | Northeast & Northern Ohio Regional Tournament | Westlake City Schools | OH |
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