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| Advanced Technologies Academy | C | 1 | State Competition | Clark County School District | NV | |
| Birmingham Groves High School | C | 1 | MI Regional 06 | Birmingham Public Schools | MI | |
| Brighton High School | C | 2 | MI Regional 11 | Brighton Area Schools | MI | |
| California Academy of Mathematics and Science | C | 1 | Los Angeles - South | Long Beach Unified School District | CA | |
| Canton High School | C | 1 | MI Regional 08 | Plymouth Canton Community Schools | MI | |
| Castro Valley High School | C | 1 | Bay Area Science Olympiad | Castro Valley Unified School District | CA | |
| Cypress Falls High School | C | 2 | San Antonio Regional | Cypress Fairbanks ISD | TX | |
| Detroit Country Day School | C | 3 | MI Regional 06 | DCDS | MI |
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| Eisenhower High Scool | C | 1 | MI Regional 7 | Utica Community Schools | MI | |
| Farmington High School | C | 1 | MI Regional 06 | Farmington Public Schools | MI | |
| Garnet Valley High School | C | 1 | Mini Satellite Hybrid SO Regional | Garnet Valley School District | PA | |
| Grosse Pointe South High School | C | 2 | MI Regional 08 | Grosse Pointe Public School District | MI | |
| Hamilton High School | C | 1 | MI Regional 10 | Hamilton Community Schools | MI | |
| Hartland High School | C | 1 | MI Regional 06 | Hartland Consolidated Schools | MI | |
| International Academy East | C | 2 | MI Regional 06 | Troy School District | MI | |
| International Academy West | C | 2 | MI Regional 06 | Huron Valley | MI | |
| Kalamazoo Area Math and Science Center | C | 2 | MI Regional 10 | Kalamazoo Public Schools | MI | |
| Kutztown Area High School | C | 1 | Mini Satellite Hybrid SO Regional | Kutztown Area School District | PA | |
| L'Anse Creuse High School | C | 1 | MI Regional 07 | L'Anse Creuse Public Schools | MI | |
| Manalapan HS | C | 1 | | Freehold Regional High School District | NJ | |
| Mentor High School | C | 2 | Northeast Ohio Regional Tournament | Mentor Public Schools | OH | |
| Northview High School | C | 3 | OHSO West Regional | Sylvania Schools | OH |
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| Northville High School | C | 2 | | Northville | MI |
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| Novi High School | C | 2 | MI Regional 06 | Novi Community School District | MI | |
| Plymouth High School | C | 1 | MI Regional 08 | Plymouth-Canton Community Schools | MI | |
| Reservoir HS | C | 2 | Eastern Maryland Region; Div. C | Howard County | MD | |
| Robinson Secondary | C | 1 | Second VA Regional (2/6) | Fairfax County Public Schools | VA |
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| Saint Anthony's High School | C | 1 | St. Anthony's High School | South Huntington | NY | |
| Saline High School | C | 1 | MI Regional 09 | Saline Area Schools | MI | |
| Skyline High School | C | 1 | MI Regional 09 | Ann Arbor Public Schools | MI | |
| Treasure Valley Homeschool Science Olympiad Team | C | 1 | Idaho | homeschool | ID |
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| Troy Athens High School | C | 2 | MI Regional 06 | Troy Schools | MI | |
| Utica High School | C | 1 | MI Regional 7 | Utica Community Schools | MI | |
| Van Nuys High School | C | | Los Angeles - South | Los Angeles Unified School District | CA | |
| William G. Enloe High School | C | 1 | North Carolina | Wake County | NC | |